Despite the diverse technical options available to help you publish your digital book, the e-book market is really dominated by three formats. While Amazon is going its own way with KF8, all the other big players in the e-book industry have opted for ePUB. This creates a problem for authors and publishers: if you publish books in the Amazon format, you can only reach users of the Kindle series and the corresponding Kindle reader apps. The reach is greater for e-books published in ePUB format. But by using ePUB, you’re committing to ignore the market leader and the biggest online retailer in the US, because ePUB-formatted e-books can’t be opened on Kindle devices or apps.
There is an alternative: PDF. The Portable Document Format is supported by all modern e-book readers and so can be viewed – in theory at least – on PCs, laptops, tablets, and smartphones. But there’s a catch to the lack of platform optimization: PDFs have a very rigid layout and don’t always immediately fit to every display screen size. This causes the most issues on mobile devices like smartphones, where there are a number of slightly differently sized small-screen displays. So if you want to focus on e-book readers specifically, it’s worth considering publishing your electronic book in one or both of the specialized formats, KF8 and ePUB. But if your content is designed to be read on a PC first and foremost, perhaps even to be printed out, then the flexible PDF format is a very good option.
The question of the distribution channel is also relevant. If you want to take advantage of the Amazon network and its huge customer base, then you’ll need to use their KF8 format. The same is true of Apple iBooks as well as other e-book shops – even ones that don’t use their own proprietary format.